Non-Invasive Ultrasonic Thalamic Stimulation in Disorders of Consciousness After Severe Brain Injury: A First-in-Man Report News Non-Invasive Ultrasonic Thalamic Stimulation in Disorders of Consciousness After Severe Brain Injury: A First-in-Man Report
BrainSonix Celebrates Dr. Edythe D. London on BMMRO Grant Award for the First LIFUP-PET Study in Smoking Cessation! Press BrainSonix Celebrates Dr. Edythe D. London on BMMRO Grant Award for the First LIFUP-PET Study in Smoking Cessation!
BrainSonix Congratulates Dr. Susan Bookheimer on Her NIH R01 for Alzheimer’s Disease and Mild Cognitive Impairment Research! Press BrainSonix Congratulates Dr. Susan Bookheimer on Her NIH R01 for Alzheimer’s Disease and Mild Cognitive Impairment Research!
Dr. Martin Monti Earns New Funding Using BrainSonix LIFUP to Treat Disorders of Consciousness Press Dr. Martin Monti Earns New Funding Using BrainSonix LIFUP to Treat Disorders of Consciousness
BrainSonix Applauds Dr. Norman Spivak on his NIH Research Grant! Press BrainSonix Applauds Dr. Norman Spivak on his NIH Research Grant!
Low-Intensity Transcranial Focused Ultrasound Amygdala Neuromodulation: Target Engagement and Early Clinical Evaluation News Low-Intensity Transcranial Focused Ultrasound Amygdala Neuromodulation: Target Engagement and Early Clinical Evaluation
Histological Examination of Focused Ultrasound Effects on Human Brain Tissue News Histological Examination of Focused Ultrasound Effects on Human Brain Tissue
Preliminary Examination of the Effects of Focused Ultrasound on Living Skin and Temperature at the Skin–Transducer Interface News Preliminary Examination of the Effects of Focused Ultrasound on Living Skin and Temperature at the Skin–Transducer Interface
This paper described the design and operational framework of a clinically deployable low-intensity focused ultrasound pulsation system, the BrainSonix BX Pulsar 1002. The system was engineered explicitly for human neuromodulation, with an emphasis on calibration accuracy, reproducibility, and built-in safety controls rather than maximal acoustic output. At a time when many ultrasound systems were bespoke laboratory tools, this work articulated what was required for clinical-grade deployment. Key contributions included a single-element transducer architecture with well-characterized focal properties, defined operating envelopes, and real-time monitoring to ensure consistent delivery across sessions and operators. These design principles enabled the transition of focused ultrasound neuromodulation from experimental feasibility to scalable, multi-site clinical research. The BX Pulsar 1002 operationalized these concepts into a turnkey system, supporting standardized protocols and broader adoption across clinical and research settings. Blog This paper described the design and operational framework of a clinically deployable low-intensity focused ultrasound pulsation system, the BrainSonix BX Pulsar 1002. The system was engineered explicitly for human neuromodulation, with an emphasis on calibration accuracy, reproducibility, and built-in safety controls rather than maximal acoustic output. At a time when many ultrasound systems were bespoke laboratory tools, this work articulated what was required for clinical-grade deployment. Key contributions included a single-element transducer architecture with well-characterized focal properties, defined operating envelopes, and real-time monitoring to ensure consistent delivery across sessions and operators. These design principles enabled the transition of focused ultrasound neuromodulation from experimental feasibility to scalable, multi-site clinical research. The BX Pulsar 1002 operationalized these concepts into a turnkey system, supporting standardized protocols and broader adoption across clinical and research settings.
Design, Development, and Operation of a Low-Intensity Focused Ultrasound Pulsation (LIFUP) System for Clinical Use News Design, Development, and Operation of a Low-Intensity Focused Ultrasound Pulsation (LIFUP) System for Clinical Use
